Chosen Solution
My X52 pro acts up in certain throttle positions. the rotator axis will change and loose accuracy in certain positions with the throttle Axis and some of the buttsons stop working as well. I believe it may be an issue with its internal potentiometers but I’m not entirely sure. And to add to this I’ve owned this X52Pro for about two years now.
I AM PHOENIX that will depend which buttons etc. I suggest that you disassemble it using this guide Saitek X52 Pro Disassembly and take a look at anything that may cause a mechanical reason for it binding. If there is none you will have to consider replacing the pots. This video might help you with that task.